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Karyopharm Therapeutics - 12 Year Stock Price History | KPTI

Historical daily share price chart and data for Karyopharm Therapeutics since 2013 adjusted for splits and dividends. The latest closing stock price for Karyopharm Therapeutics as of July 16, 2025 is 4.18.
  • The all-time high Karyopharm Therapeutics stock closing price was 706.80 on June 13, 2014.
  • The Karyopharm Therapeutics 52-week high stock price is 16.94, which is 305.3% above the current share price.
  • The Karyopharm Therapeutics 52-week low stock price is 3.51, which is 16% below the current share price.
  • The average Karyopharm Therapeutics stock price for the last 52 weeks is 9.14.
For more information on how our historical price data is adjusted see the Stock Price Adjustment Guide.
  
Karyopharm Therapeutics Historical Annual Stock Price Data
Year Average Stock Price Year Open Year High Year Low Year Close Annual % Change
2025 6.5126 12.1740 12.4350 3.5400 4.1800 -58.80%
2024 14.6075 13.5180 24.9000 8.9250 10.1445 -21.82%
2023 31.9730 48.9000 68.8500 10.1370 12.9750 -74.56%
2022 89.8874 106.5000 215.7000 37.2000 51.0000 -47.12%
2021 138.9610 253.8000 265.3500 66.7500 96.4500 -58.46%
2020 261.7355 280.8000 415.8000 212.1000 232.2000 -19.25%
2019 136.4331 143.4000 294.9750 61.8000 287.5500 104.59%
2018 223.2481 148.8000 317.7000 123.0000 140.5500 -2.40%
2017 153.0592 144.6000 207.6000 121.8000 144.0000 2.13%
2016 124.0330 201.9000 205.5000 79.9500 141.0000 -29.06%
2015 335.3277 569.8500 569.8500 155.5500 198.7500 -64.60%
2014 526.6548 345.1500 706.8000 323.5500 561.4500 63.31%
Sector Industry Market Cap Revenue
Medical Medical - Drug Manufacturing $0.037B $0.145B
Karyopharm Therapeutics, Inc. is a clinical-stage pharmaceutical company focused on the discovery and development of drugs for the treatment of cancer and other major diseases. It serves the healthcare industry throughout the United States. Karyopharm Therapeutics, Inc. is based in United States.
Stock Name Country Market Cap PE Ratio
Chugai Pharmaceutical (CHGCY) Japan $75.266B 28.24
Zoetis (ZTS) United States $68.055B 25.39
Takeda Pharmaceutical (TAK) Japan $46.933B 9.34
Daiichi Sankyo, - (DSNKY) Japan $43.096B 22.09
BeOne Medicines - (ONC) Cayman Islands $29.559B 0.00
Sandoz Group AG (SDZNY) Switzerland $24.954B 0.00
Summit Therapeutics (SMMT) United States $18.091B 0.00
Merck (MKKGY) Germany $16.498B 12.09
Shionogi (SGIOY) Japan $14.172B 14.20
United Therapeutics (UTHR) United States $13.227B 11.70
Neurocrine Biosciences (NBIX) United States $12.988B 44.49
Orion OYJ (ORINY) Finland $10.973B 29.68
IPSEN (IPSEY) France $10.239B 0.00
Stevanato Group S.p.A (STVN) Italy $7.753B 47.41
Corcept Therapeutics (CORT) United States $7.573B 61.56
Madrigal Pharmaceuticals (MDGL) United States $6.908B 0.00
Grifols, S.A (GRFS) Spain $6.717B 0.00
Ionis Pharmaceuticals (IONS) United States $6.685B 0.00
Hikma Pharmaceuticals Plc (HKMPF) United Kingdom $6.153B 0.00
Ono Pharmaceutical (OPHLF) Japan $5.265B 16.01
Soleno Therapeutics (SLNO) United States $4.212B 0.00
Hypermarcas (HYPMY) Brazil $3.167B 20.83
Crinetics Pharmaceuticals (CRNX) United States $2.980B 0.00
AMNEAL PHARMACEUTICALS, INC (AMRX) United States $2.592B 14.02
Catalyst Pharmaceuticals (CPRX) United States $2.555B 8.95
NewAmsterdam Pharma (NAMS) Netherlands $2.360B 0.00
Centessa Pharmaceuticals (CNTA) United Kingdom $2.014B 0.00
BioCryst Pharmaceuticals (BCRX) United States $1.825B 0.00
Ocular Therapeutix (OCUL) United States $1.767B 0.00
ARS Pharmaceuticals (SPRY) United States $1.725B 0.00
Endo (NDOI) United States $1.602B 0.00
Evotec AG (EVO) Germany $1.491B 0.00
Guardian Pharmacy Services (GRDN) United States $1.301B 0.00
Harrow (HROW) United States $1.261B 0.00
Aurinia Pharmaceuticals Inc (AUPH) Canada $1.215B 24.30
Ardelyx (ARDX) United States $1.077B 0.00
Enliven Therapeutics (ELVN) United States $1.062B 0.00
Collegium Pharmaceutical (COLL) United States $1.028B 5.55
Akebia Therapeutics (AKBA) United States $1.019B 0.00
Avadel Pharmaceuticals (AVDL) Ireland $1.004B 0.00
ProKidney (PROK) United States $0.986B 0.00
Verve Therapeutics (VERV) United States $0.982B 0.00
Dyne Therapeutics (DYN) United States $0.941B 0.00
Xeris Biopharma Holdings (XERS) United States $0.827B 0.00
Cronos Group (CRON) Canada $0.779B 0.00
KalVista Pharmaceuticals (KALV) United States $0.758B 0.00
Amylyx Pharmaceuticals (AMLX) United States $0.724B 0.00
Zevra Therapeutics (ZVRA) United States $0.699B 0.00
Xencor (XNCR) United States $0.601B 0.00
Relay Therapeutics (RLAY) United States $0.600B 0.00
USANA Health Sciences (USNA) United States $0.583B 12.68
Theravance Biopharma (TBPH) United States $0.577B 0.00
Elite Pharmaceuticals (ELTP) United States $0.568B 0.00
Bioventus (BVS) United States $0.542B 13.75
Oruka Therapeutics (ORKA) United States $0.534B 0.00
Organogenesis (ORGO) United States $0.511B 0.00
Siga Technologies (SIGA) United States $0.479B 10.00
Tourmaline Bio (TRML) United States $0.477B 0.00
Aquestive Therapeutics (AQST) United States $0.399B 0.00
Savara (SVRA) United States $0.396B 0.00
Altimmune (ALT) United States $0.339B 0.00
Rigel Pharmaceuticals (RIGL) United States $0.338B 9.13
Tonix Pharmaceuticals Holding (TNXP) United States $0.325B 0.00
Heron Therapeutics (HRTX) United States $0.311B 0.00
AleAnna (ANNA) United States $0.305B 0.00
Aldeyra Therapeutics (ALDX) United States $0.298B 0.00
Nektar Therapeutics (NKTR) United States $0.295B 0.00
Nature's Sunshine Products (NATR) United States $0.276B 25.34
Nanobiotix S.A (NBTX) France $0.251B 0.00
OmniAb (OABI) United States $0.238B 0.00
Esperion Therapeutics (ESPR) United States $0.224B 0.00
MediWound (MDWD) Israel $0.216B 0.00
Larimar Therapeutics (LRMR) United States $0.202B 0.00
China SXT Pharmaceuticals (SXTC) China $0.194B 0.00
4D Molecular Therapeutics (FDMT) United States $0.193B 0.00
Galectin Therapeutics (GALT) United States $0.177B 0.00
Profound Medical (PROF) Canada $0.171B 0.00
Aclaris Therapeutics (ACRS) United States $0.165B 0.00
Journey Medical (DERM) United States $0.163B 0.00
Liminatus Pharma (LIMN) United States $0.145B 0.00
Avita Medical (RCEL) United States $0.141B 0.00
Lexeo Therapeutics (LXEO) United States $0.137B 0.00
Lyell Immunopharma (LYEL) United States $0.135B 0.00
Inhibikase Therapeutics (IKT) United States $0.134B 0.00
Korro Bio (KRRO) United States $0.119B 0.00
Protara Therapeutics (TARA) United States $0.118B 0.00
Ironwood Pharmaceuticals (IRWD) United States $0.111B 0.00
Innate Pharma SA (IPHYF) France $0.110B 0.00
Champions Oncology (CSBR) United States $0.108B 17.73
Cardiol Therapeutics (CRDL) Canada $0.107B 0.00
Cassava Sciences (SAVA) United States $0.100B 0.00
Corbus Pharmaceuticals Holdings (CRBP) United States $0.099B 0.00
Jupiter Neurosciences (JUNS) United States $0.098B 0.00
Achieve Life Sciences (ACHV) Canada $0.092B 0.00
Nutriband (NTRB) United States $0.090B 0.00
Vivani Medical (VANI) United States $0.090B 0.00
VAXART, INC (VXRT) United States $0.085B 0.00
ESSA Pharma (EPIX) Canada $0.083B 0.00
Arch Biopartners (ACHFF) Canada $0.082B 0.00
Metagenomi (MGX) United States $0.078B 0.00
Rafael Holdings (RFL) United States $0.077B 0.00
Dominari Holdings (DOMH) United States $0.076B 0.00
Verrica Pharmaceuticals (VRCA) United States $0.074B 0.00
Fractyl Health (GUTS) United States $0.073B 0.00
Surrozen (SRZN) United States $0.072B 0.00
Pyxis Oncology (PYXS) United States $0.072B 0.00
PMV Pharmaceuticals (PMVP) United States $0.069B 0.00
Context Therapeutics (CNTX) United States $0.066B 0.00
Inotiv (NOTV) United States $0.064B 0.00
Assertio Holdings (ASRT) United States $0.063B 0.00
Klotho Neurosciences (KLTO) United States $0.062B 0.00
Allergy Therapeutics (AGYTF) United Kingdom $0.059B 0.00
Unicycive Therapeutics (UNCY) United States $0.058B 0.00
Wellgistics Health (WGRX) United States $0.058B 0.00
NRx Pharmaceuticals (NRXP) United States $0.054B 0.00
Cumberland Pharmaceuticals (CPIX) United States $0.052B 38.89
Avalo Therapeutics (AVTX) United States $0.052B 0.00
ElectroCore (ECOR) United States $0.052B 0.00
Gain Therapeutics (GANX) United States $0.051B 0.00
Century Therapeutics (IPSC) United States $0.050B 0.00
Prelude Therapeutics (PRLD) United States $0.046B 0.00
Mural Oncology (MURA) Ireland $0.043B 0.00
Acrivon Therapeutics (ACRV) United States $0.040B 0.00
Vivos Therapeutics (VVOS) United States $0.040B 0.00
Iterum Therapeutics (ITRM) Ireland $0.039B 0.00
PolyPid (PYPD) Israel $0.036B 0.00
Telomir Pharmaceuticals (TELO) United States $0.034B 0.00
SCYNEXIS (SCYX) United States $0.030B 0.00
FibroGen (FGEN) United States $0.030B 0.00
Enlivex Therapeutics (ENLV) Israel $0.029B 0.00
Tempest Therapeutics (TPST) United States $0.025B 0.00
Scienture Holdings (SCNX) United States $0.022B 0.00
Natural Alternatives (NAII) United States $0.021B 0.00
Relmada Therapeutics (RLMD) United States $0.021B 0.00
VYNE Therapeutics (VYNE) United States $0.020B 0.00
BioLineRx (BLRX) Israel $0.019B 0.00
Reviva Pharmaceuticals Holdings (RVPH) United States $0.019B 0.00
MARKER THERAPEUTICS, INC (MRKR) United States $0.018B 0.00
Citius Pharmaceuticals (CTXR) United States $0.017B 0.00
ProPhase Labs (PRPH) United States $0.017B 0.00
Carisma Therapeutics (CARM) United States $0.017B 0.00
DURECT (DRRX) United States $0.016B 0.00
Plus Therapeutics (PSTV) United States $0.016B 0.00
Lipocine (LPCN) United States $0.016B 0.00
CASI Pharmaceuticals (CASI) China $0.016B 0.00
Mannatech (MTEX) United States $0.016B 0.00
Ernexa Therapeutics (ERNA) United States $0.014B 0.00
TherapeuticsMD (TXMD) United States $0.013B 0.00
BioVie (BIVI) United States $0.013B 0.00
Cosmos Health (COSM) United States $0.013B 0.00
Minerva Neurosciences (NERV) United States $0.013B 2.21
Ainos (AIMD) United States $0.012B 0.00
Phio Pharmaceuticals (PHIO) United States $0.011B 0.00
Lyra Therapeutics (LYRA) United States $0.011B 0.00
Incannex Healthcare (IXHL) Australia $0.010B 0.00
Addex Therapeutics (ADXN) Switzerland $0.010B 0.00
Kiora Pharmaceuticals (KPRX) United States $0.009B 0.00
Talphera (TLPH) United States $0.009B 0.00
XTL Biopharmaceuticals (XTLB) Israel $0.009B 0.00
Traws Pharma (TRAW) United States $0.008B 0.00
NLS Pharmaceutics (NLSP) Switzerland $0.008B 0.00
Biomerica (BMRA) United States $0.008B 0.00
Mangoceuticals (MGRX) United States $0.008B 0.00
Nuvilex (PMCB) United States $0.008B 0.00
TransCode Therapeutics (RNAZ) United States $0.007B 0.00
Indaptus Therapeutics (INDP) United States $0.007B 0.00
Sonoma Pharmaceuticals (SNOA) United States $0.006B 0.00
Qualigen Therapeutics (QLGN) United States $0.006B 0.00
Xenetic Biosciences (XBIO) United States $0.006B 0.00
Alaunos Therapeutics (TCRT) United States $0.006B 0.00
Aptorum Group (APM) United Kingdom $0.005B 0.00
Quoin Pharmaceuticals (QNRX) United States $0.005B 0.00
Redhill Biopharma (RDHL) Israel $0.004B 0.00
Clearmind Medicine (CMND) Canada $0.004B 0.00
SciSparc (SPRC) Israel $0.004B 0.00
SHINECO (SISI) China $0.004B 0.00
Galmed Pharmaceuticals (GLMD) Israel $0.003B 0.00
InMed Pharmaceuticals (INM) Canada $0.003B 0.00
CERo Therapeutics Holdings (CERO) United States $0.003B 0.00
XORTX Therapeutics (XRTX) Canada $0.003B 0.00
PainReform (PRFX) Israel $0.003B 0.00
60 Degrees Pharmaceuticals (SXTP) United States $0.003B 0.00
Aditxt (ADTX) United States $0.002B 0.00
Jaguar Animal Health (JAGX) United States $0.002B 0.00
Heatwurx (PCSA) United States $0.002B 0.00
Shuttle Pharmaceuticals Holdings (SHPH) United States $0.002B 0.00
Conduit Pharmaceuticals (CDT) United States $0.002B 0.00
TNF Pharmaceuticals (TNFA) United States $0.002B 0.00
Salarius Pharmaceuticals (SLRX) United States $0.001B 0.00
Universe Pharmaceuticals INC (UPC) China $0.000B 0.00
Indivior (INDV) United States $0.000B 8.99
4D Pharma (LBPS) United Kingdom $0.000B 0.00
MEI Pharma (MEIP) United States $0.000B 0.00
Patheon (PTHN) Netherlands $0.000B 0.00
RVL Pharmaceuticals (RVLP) United States $0.000B 0.00
Silence Therapeutics (SLN) United Kingdom $0.000B 0.00